Purpuric lesions: what diagnosis?

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چکیده

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Pigmented purpuric dermatoses.

Pigmented purpuric dermatoses (PPD) are a group of histopathologically similar conditions that are primarily differentiated based on morphology. The basic pathological finding is a lymphocytic perivascular infiltrate with hemorrhage limited to the papillary dermis without fibrinoid necrosis of the vessels. The etiology is unknown; they run a chronic course and are fairly resistant to treatment....

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Pigmented Purpuric Dermatoses

The aetiology is unknown but important contributory factors include venous hypertension, exercise and gravitational dependency [2] . Histology shows a perivascular lymphocytic infiltrate of T cells centred on the superficial small blood vessels of the skin, suggesting that cell-mediated immunity plays a part [3] . There is swelling of endothelial cells and narrowing of the lumen. Extravasation ...

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ژورنال

عنوان ژورنال: BMJ Case Reports

سال: 2016

ISSN: 1757-790X

DOI: 10.1136/bcr-2015-210154